[Federal Register: April 16, 2007 (Volume 72, Number 72)]
[Notices]               
[Page 18999]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr16ap07-90]                         

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

 
National Toxicology Program (NTP); Report on Carcinogens Review 
Process for the 12th Report on Carcinogens (RoC)

AGENCY: National Institute of Environmental Health Sciences (NIEHS), 
National Institutes of Health (NIH), Department of Health and Human 
Services.

ACTION: Notice.

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SUMMARY: The NTP announces its scientific review process to review 
nominations for the 12th RoC. The process is available on the NTP Web 
site http://ntp.niehs.nih.gov (select ``Report on Carcinogens'') or by 

contacting Dr. C.W. Jameson at the address provided below.

ADDRESSES: All correspondence should be directed to Dr. C.W. Jameson, 
National Toxicology Program, Report on Carcinogens, 79 Alexander Drive, 
Building 4401, Room 3118, P.O. Box 12233, Research Triangle Park, NC 
27709; telephone: (919) 541-4096, fax: (919) 541-0144, e-mail: 
jameson@niehs.nih.gov.


SUPPLEMENTARY INFORMATION: 

Background

    On August 17, 2006, the NTP released its draft review process 
applicable for nominations to the 12th RoC (71 FR 47507) and invited 
public comment. The NTP considered all comments received and now 
announces the final RoC review process for the 12th RoC. Two important 
elements in the RoC review process are (1) the public peer review of 
draft background documents by ad hoc scientific expert panels and (2) 
the public peer review of draft substance profiles by the NTP Board of 
Scientific Counselors. In addition, the NTP will also, on a trial 
basis, prepare a response to public comments for the 12th RoC. The RoC 
review process is described in more detail on the NTP Web site (http://ntp.niehs.nih.gov/
 select ``Report on Carcinogens'').


Background Information on the Report on Carcinogens

    The RoC is a congressionally mandated document (Section 301(b)(4) 
of the Public Health Services Act, 42 U.S.C. 241(b)(4)), published by 
the Secretary of Health and Human Services (HHS), that identifies 
agents, substances, mixtures, or exposure circumstances (collectively 
referred to as ``substances'') that may pose a carcinogenic hazard to 
human health. The Secretary, HHS, has delegated responsibility for 
preparing the draft report to the NTP. Substances are listed in the RoC 
as either known to be a human carcinogen or reasonably anticipated to 
be a human carcinogen. Review of nominations involves a multi-step 
scientific review process with opportunity for public comment. At the 
end of this process, NTP forwards a draft RoC to the Secretary for 
review, approval, and transmittal to Congress and the public.
    The NTP solicits and encourages the broadest participation from 
interested individuals or parties in nominating substances for review 
for future RoCs. Nominations should contain a rationale for review. 
Appropriate background information and relevant data [e.g., journal 
articles, NTP Technical Reports, International Agency for Research on 
Cancer (IARC) listings, exposure surveys, release inventories, etc.] 
that support the review of a nomination should be provided or 
referenced when possible. Contact information for the nominator should 
also be included [name, affiliation (if any), address, telephone, fax, 
and e-mail].

    Dated: March 19, 2007.
David A. Schwartz,
Director, National Institute of Environmental Health Science and 
National Toxicology Program.
[FR Doc. E7-7111 Filed 4-13-07; 8:45 am]

BILLING CODE 4140-01-P